More articles from Volume 5, Issue 2, 2016
Assessment of nutritional composition in elephant foot yam (Amorphophallus paeoniifolius Dennst- Nicolson) cultivars
Modeling the kinetics of peroxidase inactivation, colour and texture changes of Portuguese cabbage (Brassica oleracea L. var. costata DC) during UV-C light and heat blanching
Reproducibility and correlation between meat shear force measurements by Warner-Bratzler machine and a texturometer
Natural antioxidants isolated from Schinus areira leaves by ultrasound-assisted extraction
Solubility of Stevioside and Rebaudioside A in water, ethanol and their binary mixtures
Citations
20
Jingwen Cui, Margareta Sandahl, Ola F. Wendt, Irene Rodriguez‐Meizoso
(2019)
Extraction with Water‐in‐Carbon Dioxide Microemulsions: A Case Study on Steviol Glycosides
Journal of Surfactants and Detergents, 22(6)
10.1002/jsde.12325
Zhenguang Liu, Zexiang Ding, Yifeng Cao, Baojian Liu, Qiwei Yang, Zhiguo Zhang, Qilong Ren, Zongbi Bao
(2024)
Temperature-dependent solubility of Rebaudioside A in methanol/ethanol and ethyl acetate mixtures: Experimental measurements and thermodynamic modeling
Chinese Journal of Chemical Engineering, 72()
10.1016/j.cjche.2024.05.020
Asma Romdhani, Fleming Martínez, Ovidio A. Almanza, María A. Peña, Abolghasem Jouyban, William E. Acree
(2019)
Solubility of sulfacetamide in (ethanol + water) mixtures: Measurement, correlation, thermodynamics, preferential solvation and volumetric contribution at saturation
Journal of Molecular Liquids, 290()
10.1016/j.molliq.2019.111219
Djéssica Tatiane Raspe, Camila da Silva, Silvio Cláudio da Costa
(2023)
Pressurized liquid extraction of compounds from Stevia leaf: Evaluation of process variables and extract characterization
The Journal of Supercritical Fluids, 193()
10.1016/j.supflu.2022.105813
Zhuoyu Zhou, Wanjie Wang, Qinbing Guo, Haijun Wang, Yongmei Xia
(2025)
Structure–Property Relevance of Two Pairs of Isomeric Steviol Rebaudiosides and the Underlying Mechanism
Foods, 14(11)
10.3390/foods14111917
Uswatun Hasanah Zaidan, Nur Izzati Mohamad Zen, Nor Aida Amran, Suhaili Shamsi, Siti Salwa Abd Gani
(2019)
Biochemical evaluation of phenolic compounds and steviol glycoside from Stevia rebaudiana extracts associated with in vitro antidiabetic potential
Biocatalysis and Agricultural Biotechnology, 18()
10.1016/j.bcab.2019.101049
Ye-Lim Park, Mi-Sun Lee, Sung-Hee Park
(2025)
In vitro metabolism study of α-1,6-glucosylated steviol glycosides
Food Science and Biotechnology, 34(15)
10.1007/s10068-025-01959-z
Habiba Samreen, Suneela Dhaneshwar
(2023)
Artificial Sweeteners: Perceptions and Realities
Current Diabetes Reviews, 19(7)
10.2174/1573399818666220429083052
Behnaz Asadzadeh, Jialun Zhong, Weidong Yan
(2018)
Solid–Liquid Equilibrium of Rebaudioside A in Pure and Binary Mixed Solvents at T = (288.15 to 328.15) K
Journal of Chemical & Engineering Data, 63(11)
10.1021/acs.jced.8b00780
Judy Retti Witono, Andy Chandra
(2020)
The Study on the Method for Maximizing Steviol Glycoside Extract from Stevia Leaves
IOP Conference Series: Materials Science and Engineering, 742()
10.1088/1757-899X/742/1/012048
Liliana Celaya, Pablo Martina, Nicolás Kolb-Koslobsky
(2022)
Infusions prepared with Stevia rebaudiana: application of a simplex centroid mixture design for the study of natural sweeteners and phenolic compounds
Journal of Food Science and Technology, 59(1)
10.1007/s13197-021-04979-9
Djéssica Tatiane Raspe, Simone Rocha Ciotta, Maria Rosa Trentin Zorzenon, Antônio Sergio Dacome, Camila da Silva, Paula Gimenez Milani, Silvio Cláudio da Costa
(2021)
Ultrasound-assisted extraction of compounds from Stevia leaf pretreated with ethanol
Industrial Crops and Products, 172()
10.1016/j.indcrop.2021.114035
Bárbara E. Meza, Juan Manuel Peralta
(2023)
Moisture sorption isotherms of reduced‐sugar confectionery coatings elaborated with stevia: Mathematical modeling and thermodynamic analysis
Journal of Food Process Engineering, 46(9)
10.1111/jfpe.14402
Liliana Celaya, Nicolás Kolb Koslobsky
(2024)
Effect of Ethyl Acetate on the Defatting of Leaves in the Extraction of Stevia rebaudiana Bertoni
Food Technology and Biotechnology, 62(3)
10.17113/ftb.62.03.24.8492
Yaxian Liu, Xiao Hua, Menglei Zhang, Aibin Zhou, Xiangyun Zhou, Ruijin Yang
(2021)
Recovery of steviol glycosides from industrial stevia by-product via crystallization and reversed-phase chromatography
Food Chemistry, 344()
10.1016/j.foodchem.2020.128726
Jurga Andreja Kazlauskaite, Inga Matulyte, Mindaugas Marksa, Raimundas Lelesius, Alvydas Pavilonis, Jurga Bernatoniene
(2023)
Application of Antiviral, Antioxidant and Antibacterial Glycyrrhiza glabra L., Trifolium pratense L. Extracts and Myristica fragrans Houtt. Essential Oil in Microcapsules
Pharmaceutics, 15(2)
10.3390/pharmaceutics15020464
Behnaz Asadzadeh, Bingbing Liu, Weidong Yan
(2019)
Investigation of solid–liquid equilibrium of stevioside in different pure and binary mix solvents at various temperatures
Canadian Journal of Chemistry, 97(12)
10.1139/cjc-2019-0232
Ana da Rosa, Jaqueline Hoscheid, Vitor Garcia, Oscar de Oliveira Santos Junior, Camila da Silva
(2024)
Phytochemical Extract from Syzygium cumini Leaf: Maximization of Compound Extraction, Chemical Characterization, Antidiabetic and Antibacterial Activity, and Cell Viability
Processes, 12(10)
10.3390/pr12102270
Qiwei Xu, Ke Yuan, Jianhui Gu, Minghui Zhu, Hang Song
(2021)
Recovery of rebaudioside A from mother liquor sugar in industrial steviol glycoside production by adding inorganic salts
Sustainable Chemistry and Pharmacy, 20()
10.1016/j.scp.2020.100360
Loubna Mekdade, Nassim Madi, Hossem Sahraoui
(2025)
Stevia and Steviol Glycosides in Dairy Products: An Overview on Usage, Microbial Dynamics, and Gut Health Effects – a Review Article
Polish Journal of Food and Nutrition Sciences, ()
10.31883/pjfns/214748Solubility of Stevioside and Rebaudioside A in water, ethanol and their binary mixtures
,
Chemistry and Life Sciences, Faculty of Exact, National University of Misiones , Posadas , Argentina
Chemistry and Life Sciences, Faculty of Exact, National University of Misiones , Posadas , Argentina
Chemistry and Life Sciences, Faculty of Exact, National University of Misiones , Posadas , Argentina
Published: 18.10.2016.
Volume 5, Issue 2 (2016)
pp. 158-166;
Abstract
In order to investigate the solubility of Stevioside and Rebaudioside A in different solvents (ethanol, water, ethanol:water 30:70 and ethanol:water 70:30), supersaturated solutions of pre-crystalized steviol glycosides were maintained at different temperatures (from 5 °C to 50 °C) to reach equilibrium. Under these conditions significant differences were found in the extent of solubility. Rebaudioside A was poorly soluble in ethanol and water, and Stevioside was poorly soluble in water. Solvent mixtures more effectively promoted solubilisation, and a significant effect of temperature on solubility was observed. The two steviol glycosides showed higher solubilities and this behavior was promoted by the presence of the other sweetener. The polarity indices of the solvents were determined, and helped to explain the observed behavior. Several solute-solvent and solute-solute interactions can occur, along with the incidence of a strong affinity between solvents. The obtained results are in accordance with technological applications of ethanol, water and their binary mixtures for Stevioside and Rebaudioside A separations.
Keywords
References
Citation
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Article metrics
The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.
