Estimating the risk of phthalates exposure via tea consumption in general population
Mohammad Mehdi Amin
,
Mohammad Mehdi Amin
Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences,
Isfahan, Iran
Environmental Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences,
Isfahan, Iran
Environmental Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences,
Isfahan, Iran
Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences,
Isfahan, Iran
Environmental Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences,
Isfahan, Iran
Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences,
Isfahan, Iran
Environmental Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences,
Isfahan, Iran
Four common phthalic acid esters (PAEs) levels in tea fusions samples prepared from three types of tea bags (green, black and white) of ten commercial brands were extracted from the infusions by a dispersive liquid-liquid micro extraction method and determined by GC-MS. PAEs were not found in white tea samples. Residue levels of total phthalic acid esters (TPAEs) in black and green teas showed no significant difference (median=367.5, Interquartile range=244.7-667.5 and median=381, Interquartile range=188.7-688.2µg/kg respectively). DEHP levels in green teas were significantly higher than those in black teas (Median= 93.5 and 204 respectively). Total phthalate esters (TPAEs) levels in flavored teas were about two-fold higher than in non-flavored teas. The four commercial brands tested contain significant levels of DEHP when compared to other brands. Essential oils and essences that were added to tea for improvement of color and taste could be the main sources of PAEs contamination.
If oral absorption of phthalates were assumed to be 100%, the maximum daily exposure levels to TPAEs via tea consumption (due to consumption of 5 cups of tea prepared from the tea containing the highest levels TPAEs) were estimated to be 230e−4 µg/kg bw/Day, which are far lower than the regulation levels set by the expert panels on regularly toxicity.
Beizhen H, Weihua S, Liping X, Tiefeng S. Determination of 33 pesticides in tea using accelerated solvent extraction/gel permeation chromatography and solid phase extraction/gas chromatography-mass spectrometry. Journal of Chromatography. 2008. p. 22–8.
2.
Cabrera C, Artacho R, Gimenez R. Beneficial effects of green tea -a review. Journal of the American College of Nutrition. 2006. p. 79–99.
3.
Chacko S, Thambi P, Kuttan R, Nishigaki I. Beneficial effects of green tea: a literature review. Chinese Medicine. 2010. p. 13.
4.
Del Carlo M, Pepe A, Sacchetti G, Compagnone D, Mastrocola D, Cichelli A. Determination of phthalate esters in wine using solid-phase extraction and gas chromatography-mass spectrometry. Food Chemistry. 2008. p. 771–7.
5.
Di Bella G, Saitta M, La Pera L, Alfa M, Dugo G. Pesticide and plasticizer residues in bergamot essential oils from calabria (italy). Chemosphere. 2004. p. 777–82.
6.
Du L, Ma L, Qiao Y, Lu Y, Xiao D. Determination of phthalate esters in teas and tea infusions by gas chromatography-mass spectrometry. Food chemistry. 2016. p. 1200–6.
7.
Phthalates Exposure via Tea Consumption. p. 77.
8.
Ermer J, Miller J. Method validation in pharmaceutical analysis: a guide to best practice. John Wiley & Sons; 2006.
9.
Fao. Tea consumption statistics. 2015.
10.
Farahani H, Norouzi P, Dinarvand R, Ganjali M. Development of dispersive liquid-liquid microextraction combined with gas chromatography-mass spectrometry as a simple, rapid and highly sensitive method for the determination of phthalate esters in water samples. Journal of Chromatography A. 2007. p. 105–12.
11.
Glue C, Platzer M, Larsen S, Nielsen G, Skov P, Poulsen L. Phthalates potentiate the response of allergic effector cells. Basic & Clinical Pharmacology & Toxicology. 2005. p. 140–2.
12.
Gupta S, Saha B, Giri A. Comparative antimutagenic and anticlastogenic effects of green tea and black tea: a review. Mutation Research-reviews in Mutation Research. 2002. p. 37–65.
13.
Han Q, Mihara S, Fujino T. Multi-Element Detection in Green, Black, Oolong, and Pu-Erh Teas by ICP-MS. Biochem. Physiol. 2014. p. 2.
14.
Heudorf U, Mersch-Sundermann V, Angerer J. International Workshop on Childrens Environment in Central Europe -Threats and Chances. International Journal of Hygiene and Environmental Health. 2007. p. 623–34.
15.
Kamrin M. Phthalate risks, phthalate regulation, and public health: a review. Journal of Toxicology and Environmental Health-part B-critical Reviews. 2009. p. 157–74.
16.
Karimi G, Hasanzadeh M, Nili A, Khashayarmanesh Z, Samiei Z, Nazari F, et al. Concentrations and health risk of heavy metals in tea samples marketed in iran. Pharmacology. 2008. p. 164–74.
17.
Latini G. Monitoring phthalate exposure in humans. Clinica Chimica Acta. 2005. p. 20–9.
18.
Lin D, Zhu L, He W, Tu Y. Tea plant uptake and translocation of polycyclic aromatic hydrocarbons from water and around air. Journal of Agricultural and Food Chemistry. 2006. p. 3658–62.
19.
Lo Turco V, Di Bella G, Potorti A, Fede M, Dugo G. Determination of plasticizer residues in tea by solid phase extraction-gas chromatography-mass spectrometry. European Food Research and Technology. 2015. p. 451–8.
20.
Lu Y, Du L, Qiao Y, Wang T, Xiao D. Advances in applied biotechnology: proceedings of the 2nd international conference on applied biotechnology (icab 2014)volume i. Springer; 2015. p. 305–15.
21.
Martino-Andrade A, Chahoud I. Reproductive toxicity of phthalate esters. Molecular Nutrition & Food Research. 2010. p. 148–57.
22.
Mohamed M, Ammar A. Quantitative analysis of phthalates plasticizers in traditional egyptian foods (koushary and foul medams), black tea, instant coffee and bottled waters by solid phase extractioncapillary gas chromatography-mass spectroscopy. American Journal of Food Technology. 2008. p. 341–6.
23.
Montuori P, Jover E, Morgantini M, Bayona J, Triassi M. Assessing human exposure to phthalic acid and phthalate esters from mineral water stored in polyethylene terephthalate and glass bottles. Food Additives and Contaminants. 2008. p. 511–8.
24.
Qin F, Chen W. Lead and copper levels in tea samples marketed in beijing, china. Bulletin of Environmental Contamination and Toxicology. 2007. p. 247–50.
25.
Shah S, Pate V. Tea production in india: challenges and opportunities. Journal of Tea Science Research. 2016. p. 1–6.
26.
Shaltout A, Abdel-Aal M, Welz B, Castilho I. Determination of cd, cu, ni, and pb in black tea from saudi arabia using graphite furnace atomic absorption spectrometry after microwaveassisted acid digestion. Analytical Letters. 2013. p. 2089–100.
27.
Shen FM, Chen HW. Overview of phthalates toxicity. Bulletin of Environmental Contamination and Toxicology. 2008. p. 300–4.
28.
Yen TH, Lin-Tan DT, Lin JL. Food safety involving ingestion of foods and beverages prepared with phthalate-plasticizer-containing clouding agents. Journal of the Formosan Medical Association. 2011. p. 671–84.
29.
Zheng N, Wang Q, Zhang X, Zheng D, Zhang Z, Zhang S. Population health risk due to dietary intake of heavy metals in the industrial area of huludao city, china. Science of the Total Environment. 2007. p. 96–104.
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